Homing Endonucleases and Inteins by Marlene Belfort (English) Hardcover Book

Description: Homing Endonucleases and Inteins by Marlene Belfort, Barry L. Stoddard, David W. Wood, Vicky Derbyshire This book provides a comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations. Notes First book devoted exclusively to the biology and technical applications growing out of research with inteins and homing endonucleases Back Cover This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations. Table of Contents Back to Basics: Structure, Function, Evolution and Application of Homing Endonucleases and Inteins.- Homing Endonucleases and the Yeast Mitochondrial ? Locus — A Historical Perspective.- The LAGLIDADG Homing Endonuclease Family.- HNH Endonucleases.- GIY-YIG Homing Endonucleases — Beads on a String.- His-Cys Box Homing Endonucleases.- Group I Introns and Their Maturases: Uninvited, but Welcome Guests.- Group II Intron Homing Endonucleases: Ribonucleoprotein Complexes with Programmable Target Specificity.- Free-Standing Homing Endonucleases of T-even Phage: Freeloaders or Functionaries?.- Function and Evolution of HO and VDE Endonucleases in Fungi.- Engineering Homing Endonucleases for Genomic Applications.- Inteins — A Historical Perspective.- Origin and Evolution of Inteins and Other Hint Domains.- Biochemical Mechanisms of Intein-Mediated Protein Splicing.- The Structure and Function of Intein-Associated Homing Endonucleases.- Harnessing Inteins for Protein Purification and Characterization.- Production of Cyclic Proteins and Peptides.- Inteins for Split-Protein Reconstitutions and Their Applications.- Intein Reporter and Selection Systems.- Industrial Applications of Intein Technology. Feature First book devoted exclusively to the biology and technical applications growing out of research with inteins and homing endonucleases Details ISBN3540251065 Author Vicky Derbyshire Short Title HOMING ENDONUCLEASES & INTEINS Series Nucleic Acids and Molecular Biology Language English ISBN-10 3540251065 ISBN-13 9783540251064 Media Book Format Hardcover Series Number 16 Year 2005 Imprint Springer-Verlag Berlin and Heidelberg GmbH & Co. K Place of Publication Berlin Country of Publication Germany DEWEY 572.8 Edited by Vicky Derbyshire Birth 1945 Pages 377 DOI 10.1007/b94820;10.1007/3-540-29474-0 Publisher Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Publication Date 2005-10-11 Alternative 9783540852353 Illustrations XIX, 377 p. Audience Professional & Vocational Edition Description 2005 ed. Edition 2005th We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96309115;

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